RT journal article T1 Granular cell tumor in breast: A case report A1 Castillo Lara, María A1 Martínez Herrera, Antonia A1 Torrejón Cardoso, Rafael A1 Lubián López, Daniel María A2 Materno-Infantil y Radiología K1 carcinoma K1 S-protein K1 calretinin K1 PAS diastase K1 local anesthesia AB Granular cell tumor (GCT) is a rare neoplasm of the soft tissues, and <1% of all GCTs are malignant. It usually appears in the tongue and sometimes may affect the female breast. Initially, GCT was considered to be a myogenic lesion affecting female breast (myoblastoma). Actually, it is assumed as a tumor originating from perineural or putative Schwann cells of peripheral nerves or their precursors that grows in the lobular breast tissue, due to the immunohistochemical features. Here, we review the importance of differentiating between this tumor and malignant breast carcinoma. Mammographically, by ultrasound scan and clinically, this case appears to be a malignant tumor of the breast, but with a correct and precise diagnosis including histopathologic examination and immunohistochemical studies, it was correctly identified as a GCT. Case details: We present a case of a 52-year-old premenopausal woman. This report is of interest because of patient’s familial oncologic history and personal history of gynecologic cancer. This rare tumor of the breast and the special way to approach the tumor by local anesthesia makes it interesting to communicate. Conclusion: This is a case of interest because GCT located in the breast is very unusual and knowledge of GCT is required for the differential diagnosis with breast cancer. PB Dovepress SN 1179-1314 YR 2017 FD 2017 LK http://hdl.handle.net/10498/36562 UL http://hdl.handle.net/10498/36562 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 21-sep-2026