RT journal article
T1 Split-Type Assay for Wide-Range Sensitive Sensing of Ochratoxin A with Praseodymia Nanorods
A1 Jiang, Lei
A1 Han, Yaning
A1 Li, Youxun
A1 Li, Zhuang
A1 Zhu, Xiudong
A1 Liu, Zhibin
A1 Chen, Yuxue
A1 Fernández-Garcia, Susana
A1 Tang, Yongjiao
A1 Chen, Xiaowei
A2 Ciencia de los Materiales e Ingeniería Metalúrgica y Química Inorgánica
K1 Ochratoxin A
K1 Praseodymia nanorods
K1 Dual-readout
K1 Fluorometric
K1 Fluorometric
AB The ubiquitous presence of ochratoxin A (OTA), a toxic food contaminant, requires development of fast and sensitive detection tools. However, it is difficult to find a method that can address high sensitivity and wide detection range simultaneously. In this work, a sensing platform composed of praseodymia nanorods (Pr6O11-NRs) and aptamers for OTA is established. Under the dual-readout modes, this platform provides a highly sensitive detection of OTA with extra-wide range, over three orders of magnitude with limit of detection (LOD) of 0.8 ng/mL. Both fluorometric and colorimetric signals were obtained because of the excellent fluorescent quenching and oxidase-like activity of Pr6O11-NRs. This probe enables a detection range of OTA which covers the maximum acceptable levels of most foods. Real samples were tested with this method, demonstrating high sensitivity and good recoveries. This sensing strategy has great potential for an expanded application in point-of-care detection of other toxins via portable devices.
PB Elsevier
SN 0927-7757
YR 2022
FD 2022
LK http://hdl.handle.net/10498/37577
UL http://hdl.handle.net/10498/37577
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 21-sep-2026