RT journal article T1 Salivary testosterone and immunoglobulin A were increased by resistance training in adults with Down syndrome A1 Fornieles, G. A1 Rosety Rodríguez, Miguel Ángel A1 Elosegui, S. A1 Rosety, J.M. A1 Alvero-Cruz, J.R. A1 García Gómez, Natalia A1 Rosety Rodríguez, Manuel A1 Rodríguez Pareja, María Antonia A1 Toro Cebada, Rocío A1 Rosety Rodríguez, Manuel A1 Ordóñez Muñoz, Francisco Javier A1 Rosety Rodríguez, Ignacio A2 Anatomía y Embriología Humana A2 Cirugía A2 Didáctica de la Educación FísicaPlástica y Musical A2 Medicina K1 Down syndrome K1 Resistance training K1 Saliva K1 Immunoglobulin A K1 Testosterone K1 Cortisol AB This study was designed to assess the influence of resistance training on salivary immunoglobulin A (IgA) levels and hormoneprofile in sedentary adults with Down syndrome (DS). A total of 40 male adults with DS were recruited for the trial throughdifferent community support groups for people with intellectual disabilities. All participants had medical approval forparticipation in physical activity. Twenty-four adults were randomly assigned to perform resistance training in a circuit with sixstations, 3 days per week for 12 weeks. Training intensity was based on functioning in the eight-repetition maximum (8RM) testfor each exercise. The control group included 16 age-, gender-, and BMI-matched adults with DS. Salivary IgA, testosterone,and cortisol levels were measured by ELISA. Work task performance was assessed using the repetitive weighted-box-stackingtest. Resistance training significantly increased salivary IgA concentration (P=0.0120; d=0.94) and testosterone levels(P=0.0088; d=1.57) in the exercising group. Furthermore, it also improved work task performance. No changes were seen inthe controls who had not exercised. In conclusion, a short-term resistance training protocol improved mucosal immunityresponse as well as salivary testosterone levels in sedentary adults with DS. PB Associacao Brasileira de Divulgacao Cientifica SN 1414-431X YR 2014 FD 2014 LK http://hdl.handle.net/10498/38373 UL http://hdl.handle.net/10498/38373 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 08-nov-2026