RT journal article
T1 Dropout Rate of Participants in Randomized Clinical Trials That Use Virtual Reality to Train Balance and Gait in Parkinson’s Disease. A Systematic Review With Meta-analysis and Meta-regression.
A1 Garcia Parra, Artimes
A1 González Medina, Gloria
A1 Pérez Cabezas, Verónica
A1 Casuso Holgado, María Jesús
A1 Viñolo Gil, María Jesús
A1 García Muñoz, Cristina
A2 Enfermería y Fisioterapia
K1 Dropout
K1 Parkinson’s disease
K1 Virtual reality
K1 Meta-analysis
AB Virtual reality is an effective system to train balance and gait in Parkinson’s disease, but attrition of this intervention needs to be further examined. This study aims to review and meta-analyze the dropouts of participants in randomized clinical trials that used virtual reality for balance and gait training in people with Parkinson’s disease. An electronic search was conducted in PubMed, Web of Science, Scopus and CINAHL. The PEDro scale and Revised Cochrane risk-of-bias tool for randomized trials 2.0 were employed to assess methodological quality. Proportions meta-analysis calculated dropout rate.Odds ratio meta-analysis under 1 indicated lower attrition in experimental participants. Meta-regression identified possible dropouts’ moderators. A total of 18 studies were included. The pooled dropout rates were 5.6% (95% CI, 3.3%-9.3%) for allgroups, 5.33% (95% CI, 3.03%-9.21%) in virtual reality, and 6.60% (95% CI, 3.84%-26.31%) in comparators. No statisticaldifferences were found in the dropout occurred between the groups (OR 0.83; 95% CI, 0.62-1.12). Number of weeks was the unique moderator (coefficient 0.129, 95% CI 0.018- 0.239; p=0.02). Our overall pooled dropout should be consideredin the sample size calculation of future studies. Adequate follow-up of the CONSORT guidelines in the loss report and theirreasons could help design suitable retention strategies
PB Springer Nature
SN 0148-5598
YR 2023
FD 2023
LK http://hdl.handle.net/10498/38481
UL http://hdl.handle.net/10498/38481
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 05-nov-2026