RT journal article
T1 Efficacy of Extracorporeal Shockwave Therapy in the Management of Chronic Diabetic Foot Ulcer: A Systematic Review and Meta-Analysis
A1 Ruiz Muñoz, María
A1 Rueda Zapata, Lidia
A1 Martínez Barrios, Francisco Javier
A1 Nováková, Tereza
A1 Lopezosa Reca, Eva
A1 González Sánchez, Manuel
A1 Fernández Torres, Raúl
A1 Galán Mercant, Alejandro
A2 Enfermería y Fisioterapia
K1 extracorporeal shockwave therapies
K1 diabetic foot disease
K1 meta-analysis
K1 ulcer treatment
K1 DFU
K1 diabetic wound
K1 diabetic foot ulcer
AB Introduction: This study will explore the effectiveness of current extracorporeal shockwave therapies in ulcer healing in diabetic foot disease compared to the standard of care. Methods: The systematic review and meta-analysis were performed following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) standard. The electronic databases WoS, EMBASE, MEDLINE Complete, CINAHL Complete, Academic Search Ultimate, AMED-The Allied and Complementary Medicine Database, Scopus and PubMed searched for the outcome rate of complete ulcer healing. The risk of bias assessment was conducted using the tool recommended by the Cochrane Collaboration (Robvis Tool). Statistical analysis included the individual and combined result of the studies, heterogeneity test, the effect size, sensitivity analysis, and publication bias tests. Results: Eight randomized controlled trials (RCTs) with a total of 672 patients were included in this study. This meta-analysis showed a higher rate of complete ulcer healing in groups receiving extracorporeal shockwave therapies (OR = 2.747 [1.965, 3.841], p < 0.01, I2 =0.02) compared to control groups. Conclusions: In conclusion, the results of this meta-analysis show that extracorporeal shockwave therapies, when used as an adjunctive treatment, demonstrate significantly higher ulcer healing rates compared to standard of care. Extracorporeal shockwave therapies should be taken into account as a valuable adjunct to standard care for diabetic foot ulcer treatment.
PB MDPI
SN 2076-3271
YR 2025
FD 2025
LK http://hdl.handle.net/10498/39394
UL http://hdl.handle.net/10498/39394
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 05-nov-2026