RT journal article
T1 IFUCISTRATEGY: A Spanish Survey on the Management of Invasive Fungal Infection (IFI) in Critically Ill Patients
A1 Zaragoza, Rafael
A1 Estella García, Ángel
A1 Nuvials, Xavier
A1 Robles Plaza, Mireya
A1 Casado Gómez, Araceli
A2 Medicina
K1 invasive fungal infection
K1 critically ill patients
K1 antifungal resistance
K1 aspergillosis
K1 candidiasis
AB Background: The objective was to identify management strategies of IFI in critically ill patients through a Spanish national survey. Methods: A cross-sectional multicentre survey among ICU specialists, experienced in IFI, was performed (22 April–25 July 2024). The survey consisted of 13 questions with four closed answers. Results: Sixty-three specialists from 51 hospitals of 16 regions completed the survey. 95% stated that, in high-risk patients with clinical suspicion of Pulmonary Aspergillosis (PA), galactomannan in BAL is performed to guide treatment. In the treatment of patients with PA and influenza, 86% declared that isavuconazole and liposomal amphotericin B are recommended treatments and in high suspicion of Aspergillus coinfection, 76% recommended empirical treatment waiting for microbiological confirmation. 90% declared that the use of Extracorporeal Membrane Oxygenation (ECMO) and Renal Replacement Therapies (RRT) could be associated with lower azole levels. Regarding intra-abdominal candidiasis, 78% that physiopathological changes in critically ill patients, reduce their entry into peritoneal fluid. Conclusions: The majority of the respondents agreed (>80%) on: In suspicion of PA, Galactomannan in BAL to guide treatment is mandatory; In case of aspergillosis and influenza, isavuconazole and liposomal amphotericin B are the recommended treatments; The use of ECMO and RRT could be associated with lower azole levels.
SN 2309-608X
YR 2026
FD 2026-05-05
LK http://hdl.handle.net/10498/40557
UL http://hdl.handle.net/10498/40557
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 15-nov-2026