TY - GEN AU - Pérez Arana, Gonzalo Martín AU - Segundo Iglesias, María del Carmen AU - Aguilar Diosdado, Manuel AU - Blandino Rosano, Manuel AU - Prada Oliveira, José Arturo A4 - Anatomía y Embriología Humana PY - 2010 SN - 0013-7227 SN - ISSN Online 1945-7170 UR - http://hdl.handle.net/10498/17524 AB - In autoimmune type 1 diabetes mellitus, proinflammatory cytokine-mediated apoptosis of beta-cells has been considered to be the first event directly responsible for beta-cell mass reduction. In the Bio-Breeding (BB) rat, an in vivo model used in the... LA - eng PB - The Endocrine Society. USA KW - Pancreas KW - Beta-cell mas KW - Exendin-4 KW - Diabetes TI - Decrease in Beta -Cell Proliferation Precedes Apoptosis during Diabetes Development in Bio-Breeding/ Worcester Rat: Beneficial Role of Exendin-4 DO - 10.1210/en.2009-1113 ER -