TY - GEN AU - Botubol Ares, José Manuel AU - Durán Peña, María Jesús AU - Hernández Galán, Rosario AU - González Collado, Isidro AU - M. Harwood, Laurence AU - Macías Sánchez, Antonio José A4 - Química Orgánica PY - 2015 UR - http://hdl.handle.net/10498/20582 AB - Solvent-free desymmetrisation of a meso-dialdehyde with chiral alcohols, led to preparation of 4- silyloxy-6-alkyloxytetrahydro-2H-pyran-2-one derivatives with a 96% de. This methodology, which yields the corresponding methyl nor-mevaldates with 99%... LA - eng PB - Elsevier KW - Botrytis cinerea KW - Desymmetrisation KW - meso-Dialdehyde KW - Nor-methyl mevaldate TI - Diastereoselective and enantioselective preparation of nor-mevaldic acid surrogates through desymmetrisation methodology. Enantioselective synthesis of (+) and (-) nor-mevalonic lactones DO - 10.1016/j.tet.2015.08.010 ER -