TY - GEN AU - Martínez de Arbulo Echevarría, Miguel AU - Vico Barranco, Inmaculada AU - Narbona Sánchez, Isaac AU - García Cózar, Francisco José AU - Miazek, Arkadiusz AU - Aguado Vidal, Enrique A4 - Biomedicina, Biotecnología y Salud Pública PY - 2020 SN - 2296-634X UR - http://hdl.handle.net/10498/23941 AB - The adaptor LAT plays a crucial role in the transduction of signals coming from the TCR/CD3 complex. Phosphorylation of some of its tyrosines generates recruitment sites for other cytosolic signaling molecules. Tyrosine 132 in human LAT is essential... LA - eng PB - FRONTIERS MEDIA SA KW - LAT KW - TCR KW - phosphorylation KW - anergy KW - IL-2 (interleukin-2) TI - Increased Protein Stability and Interleukin-2 Production of a LAT(G131D)Variant With Possible Implications for T Cell Anergy DO - 10.3389/fcell.2020.561503 ER -