TY  - GEN 
AU  - Araújo, Nuna
AU  - Viegas, Carla S. B.
AU  - Zubía Mendoza, Eva
AU  - Magalhães, Joana
AU  - Ramos, Acácio
AU  - Carvalho, Maria M.
AU  - Cruz, Henrique
AU  - Sousa, João Paulo
AU  - Blanco, Francisco J.
AU  - Vermeer, Cees
AU  - Simes, Dina C.
A4  - Química Orgánica
PY  - 2020
SN  - 1660-3397
UR  - http://hdl.handle.net/10498/24368
AB  - Osteoarthritis (OA) remains a prevalent chronic disease without effective prevention and treatment. Amentadione (YP), a meroditerpenoid purified from the alga Cystoseira usneoides, has demonstrated anti-inflammatory activity. Here, we investigated the...
LA  - eng
PB  - MDPI
KW  - osteoarthritis
KW  - amentadione
KW  - preclinical osteoarthritis models
KW  - marine compounds
KW  - Cystoseira usneoides
KW  - inflammation
KW  - mineralization
KW  - chondrocytes
KW  - synoviocytes
KW  - cartilage explants
TI  - Amentadione from the Alga Cystoseira usneoides as a Novel Osteoarthritis Protective Agent in an Ex Vivo Co-Culture OA Model
DO  - 10.3390/md18120624
ER  -