TY - GEN AU - Santiesteban Espejo, Antonio AU - Bernal-Florido, Irene AU - Pérez-Requena, José AU - Atienza Cuevas, Lidia AU - Maira González, María Nieves AU - García-Rojo, Marcial A4 - Anatomía Patológica, Biología Celular, Histología, Historia de la Ciencia, Medicina Legal y Forense y Toxicología PY - 2022 SN - 2234-943X UR - http://hdl.handle.net/10498/28799 AB - Classic Hodgkin lymphoma (cHL) constitutes the most frequent lymphoma in young adults. Its histopathology is unique as a scattered tumor population, termed Hodgkin Reed-Sternberg (HRS) cells is diluted in a prominent tumor microenvironment (TME)... LA - eng PB - FRONTIERS MEDIA SA KW - whole-slide imaging KW - classic Hodgkin lymphoma KW - digital image analysis KW - tumor microenvironment KW - Hodgkin Reed-Sternberg TI - Whole-slide image analysis identifies a high content of Hodgkin Reed-Sternberg cells and a low content of T lymphocytes in tumor microenvironment as predictors of adverse outcome in patients with classic Hodgkin lymphoma treated with ABVD DO - 10.3389/fonc.2022.1000762 ER -