TY  - GEN 
AU  - Martínez de Arbulo Echevarría, Miguel
AU  - Vico Barranco, Inmaculada
AU  - Zhang, Fanghui
AU  - Fernández Aguilar, Luis Miguel
AU  - Chotomska, Martyna
AU  - Narbona Sánchez,  Isaac
AU  - Zhang, Lichen
AU  - Malissen, Bernard
AU  - Liang, Yinming
AU  - Aguado Vidal, Enrique
A4  - Biomedicina, Biotecnología y Salud Pública
PY  - 2022
SN  - 1664-3224
UR  - http://hdl.handle.net/10498/28823
AB  - The LAT transmembrane adaptor is essential to transduce intracellular signals triggered by the TCR. Phosphorylation of its four C-terminal tyrosine residues (136, 175, 195, and 235 in mouse LAT) recruits several proteins resulting in the assembly of...
LA  - eng
PB  - FRONTIERS MEDIA SA
KW  - linker for activation of T cell
KW  - TCR (T cell receptor)
KW  - T cell development
KW  - anergy
KW  - T cell memory
KW  - T cell
TI  - Mutation of the glycine residue preceding the sixth tyrosine of the LAT adaptor severely alters T cell development and activation
DO  - 10.3389/fimmu.2022.1054920
ER  -