TY  - GEN 
AU  - Alba Delgado, Cristina
AU  - Llorca Torralba, Meritxell
AU  - Horrillo, Igor
AU  - Ortega, Jorge E.
AU  - Micó Segura, Juan Antonio
AU  - Sánchez-Blázquez, Pilar
AU  - Meana, Javier
AU  - Berrocoso Domínguez, Esther María
A4  - Anatomía Patológica, Biología Celular, Histología, Historia de la Ciencia, Medicina Legal y Forense y Toxicología
A4  - Neurociencias
A4  - Psicología
PY  - 2013
SN  - 0006-3223
SN  - 1873-2402
UR  - http://hdl.handle.net/10498/33329
AB  - Background: Patients suffering chronic pain are at high risk of suffering long-lasting emotional disturbances characterized by persistent low mood and anxiety. We propose that this might be the result of a functional impairment in noradrenergic...
LA  - eng
PB  - Elsevier
KW  - α2-adrenoceptors
KW  - depression
KW  - locus coeruleus
KW  - neuropathic pain
KW  - noradrenaline
KW  - prefrontal cortex
TI  - Chronic pain leads to concomitant noradrenergic impairment and mood disorders
DO  - 10.1016/j.biopsych.2012.06.033
ER  -