TY  - GEN 
AU  - Torres Sánchez, Sonia
AU  - da Silva Borges, Gisela
AU  - Micó Segura, Juan Antonio
AU  - Berrocoso Domínguez, Esther María
A4  - Neurociencias
A4  - Psicología
PY  - 2018
SN  - 0028-3908
UR  - http://hdl.handle.net/10498/34761
AB  - Tapentadol is an analgesic that acts as an agonist of µ opioid receptors (MOR) and that inhibits noradrenaline reuptake. Data from healthy rats show that tapentadol inhibits neuronal activity in the locus coeruleus (LC), a nucleus regulated by both...
LA  - eng
KW  - Locus coeruleus
KW  - Neuropathic pain
KW  - Opioid receptor
KW  - Streptozotocin
KW  - Tapentadol
KW  - alpha2-adrenoceptor
TI  - Opioid and noradrenergic contributions of tapentadol to the inhibition of locus coeruleus neurons in the streptozotocin rat model of polyneuropathic pain.
DO  - 10.1016/j.neuropharm.2018.03.014
ER  -