TY - GEN AU - Zumaquero, Esther AU - Stone, Sara L AU - Scharer, Christopher D AU - Jenks, Scott A AU - Nellore, Anoma AU - Mousseau, Betty AU - Rosal Vela, Antonio AU - Botta, Davide AU - Bradley, John E AU - Wojciechowski, Wojciech AU - Ptacek, Travis AU - Danila, Maria I AU - Edberg, Jeffrey C AU - Bridges, S Louis AU - Kimberly, Robert P AU - Chatham, W Winn AU - Schoeb, Trenton R AU - Rosenberg, Alexander F AU - Boss, Jeremy M AU - Sanz, Ignacio AU - Lund, Frances E A4 - Biomedicina, Biotecnología y Salud Pública PY - 2019 SN - 2050-084X UR - http://hdl.handle.net/10498/35094 AB - Although B cells expressing the IFNgR or the IFNg-inducible transcription factor T-bet promote autoimmunity in Systemic Lupus Erythematosus (SLE)-prone mouse models, the role for IFNg signaling in human antibody responses is unknown. We show that... LA - eng TI - IFNγ induces epigenetic programming of human T-bethi B cells and promotes TLR7/8 and IL-21 induced differentiation DO - 10.7554/ELIFE.41641 ER -