TY - GEN AU - Möller, Gabriele AU - Temml, Veronika AU - Cala Peralta, Antonio AU - Gruet, Océane AU - Richomme, Pascal AU - Seraphin, Denis AU - Viault, Guillaume AU - Kraus, Luisa AU - Huber-Cantonati, Petra AU - Schopfhauser, Elisabeth AU - Pachmayr, Johanna AU - Tokarz, Janina AU - Schuster, Daniela AU - Helesbeux, Jean-Jacques AU - Allen Dyar, Kenneth A4 - Química Orgánica PY - 2022 SN - 2218-1989 UR - http://hdl.handle.net/10498/35222 AB - Naturally occurring substances are valuable resources for drug development. In this respect, chalcones are known to be antiproliferative agents against prostate cancer cell lines through various mechanisms or targets. Based on the literature and... LA - eng PB - MDPI KW - chalcone KW - aldo-keto reductase KW - cancer KW - AKR1C3 KW - 17β-hydroxysteroid dehydrogenase KW - 3α-hydroxysteroid dehydrogenase KW - structure-activity relationship TI - Analogues of Natural Chalcones as Efficient Inhibitors of AKR1C3 DO - 10.3390/metabo12020099 ER -