TY - GEN AU - Gento Caro, Angela AU - Vilches Herrando, Esther AU - Garcia Morales, Victoria AU - Portillo Pacheco, Federico Luis AU - Rodríguez Bey, Guillermo AU - González Forero, David AU - Moreno López, Bernardo A4 - Biomedicina, Biotecnología y Salud Pública PY - 2021 SN - 1365-2990, 0305-1846 UR - http://hdl.handle.net/10498/37872 AB - Aims: Alterations in excitability represent an early hallmark in Amyotrophic Lateral Sclerosis (ALS). Therefore, deciphering the factors that impact motor neuron (MN) excitability offers an opportunity to uncover further aetiopathogenic mechanisms,... LA - eng PB - Wiley KW - SOD1-G93A model KW - amyotrophic lateral sclerosis KW - background potassium channels KW - excitotoxicity KW - intrinsic membrane excitability KW - lpa1/edg2/vzg1 KW - neurodegeneration KW - neuroprotection TI - Interfering with lysophosphatidic acid receptor edg2/lpa1 signalling slows down disease progression in SOD1-G93A transgenic mice DO - 10.1111/nan.12699 ER -