TY  - GEN 
AU  - Moares Fernández, Noelia del Carmen
AU  - González García, Pablo
AU  - Yi-He, Wenjie
AU  - Muñoz Miranda, Juan Pedro
AU  - Gabucio López, Antonio
AU  - Luna-Espejo, Rosa
AU  - Ocaña-Cuesta, Javier
AU  - Fernandez-Cisnal, Ricardo
AU  - Fernández-Ponce, Cecilia
AU  - García-Cózar, Francisco
A4  - Biomedicina, Biotecnología y Salud Pública
PY  - 2025
SN  - 1664-3224
UR  - http://hdl.handle.net/10498/37970
AB  - Introduction: Chimeric antigen receptor (CAR) T-cell therapy has demonstrated remarkable efficacy against multiple myeloma (MM). However, several barriers continue to limit the overall effectiveness of this approach, such as high production costs,...
LA  - eng
PB  - FRONTIERS MEDIA SA
KW  - chimeric antigen receptor
KW  - multiple myeloma
KW  - inteins
KW  - protein splicing
KW  - B-cell maturation antigen
KW  - SLAMF7
KW  - modular CAR
KW  - immunotherapy
TI  - Dual targeting of BCMA and SLAMF7 with the CARtein system: chimeric antigen receptors with intein-mediated splicing elicit specific T cell activation against multiple myeloma
DO  - 10.3389/fimmu.2025.1613222
ER  -