A Shared Biosynthetic Pathway for Botcinins and Botrylactones Revealed through Gene Deletions

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A Shared Biosynthetic Pathway for Botcinins and Botrylactones Revealed through Gene Deletions

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Title: A Shared Biosynthetic Pathway for Botcinins and Botrylactones Revealed through Gene Deletions
Author: Massaroli, Michelli; Moraga Galindo, Javier; Bastos borges, Keyller; Ramírez-Fernández, Jacinto; Viaud, Muriel; González Collado, Isidro; Durán Patrón, Rosa; Hernández Galán, Rosario
Departments: Química Orgánica
xmlui.dri2xhtml.METS-1.0.item-source: ChemBioChem 2013, 14, 132 – 136
Abstract: Isotopic labelling experiments and the study of mutants with disrupted genes encoding botcinic acid have revealed a common link in the biosynthesis of the polyketide toxins excreted by Botrytis cinerea: botcinins and botrylactones. Furthermore, the results reported here shed light on the origin of the starter unit, thereby solving a long-standing mystery in the biosynthesis of botcinins.
Subject: biosynthesis ; botcinin ; botrylactone ; Botrytis cinerea ; polyketides.
Handle: http://hdl.handle.net/10498/20544
Date: 2013

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Attribution-NonCommercial-NoDerivatives 4.0 Internacional Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivatives 4.0 Internacional