Biological activity of natural sesquiterpenoids containing a gem-dimethylcyclopropane unit

Abstract

The biological activities of aristolane, aromadendrane, ent-1,10-secoaromadendrane, 2,3- secoaromadendrane, ent-5,10-cycloaromadendrane, bicyclogermacrene, lepidozane, and maaliane terpenoids which contain the gem dimethylcyclopropyl unit are described. Particular attention is given to their anti-viral, anti-microbial and cytotoxic activities. In the main text there are 119 references covering the literature from 1963–2014. The ESI contains tables listing 332 of these terpenoids, their occurrence and biological activity together with the related references.