A prospective international Aspergillus terreus survey: an EFISG, ISHAM and ECMM joint study

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URI: http://hdl.handle.net/10498/33818

DOI: 10.1016/J.CMI.2017.04.012

ISSN: 1469-0691

ISSN: 1198-743X

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Author/s
Risslegger, B.; Zoran, T.; Lackner, M.; Aigner, M.; Sánchez-Reus, Ferrán; Rezusta, Antonio; Chowdhary, Anuradha; Taj-Aldeen, Saad J.; Arendrup, Maiken C.; Oliveri, Salvatore; Kontoyiannis, Dimitrios P.; Alastruey-Izquierdo, Ana; Lagrou, Katrien; Lo Cascio, Giuliana; Meis, Jacques F.; Buzina, Walter; Farina, Claudio; Drogari-Apiranthitou, Miranda; Grancini, Anna; Tortorano, Anna M.; Willinger, Birgit; Hamprecht, Axel; Johnson, Elizabeth; Klingspor, Lena; Arsic-Arsenijevic, Valentina; Cornely, Oliver A.; Meletiadis, Joseph; Prammer, Wolfgang; Tullio, Vivian; Vehreschild, Jörg-Janne; Trovato, Laura; Lewis, Russell E.; Segal, Esther; Rath, Peter-Michael; Hamal, Petr; Rodríguez Iglesias, Manuel AntonioAuthority UCA; Roilides, Emmanuel; Arikan-Akdagli, Sevtap; Chakrabarti, Arunaloke; Colombo, Arnaldo L.; Fernández, M. S.; Martin-Gomez, M. Teresa; Badali, Hamid; Petrikkos, Georgios; Klimko, Nikolai; Heimann, Sebastian M.; Houbraken, Jos; Uzun, Omrum; Edlinger, M.; de la Fuente, Sarah; Lass-Flörl, Cornelia
Date
2017
Department
Biomedicina, Biotecnología y Salud Pública
Source
Clinical Microbiology and Infection - 2017, Vol. 23 n. 10 pp. 776.e1-776.e5
Abstract
Objectives A prospective international multicentre surveillance study was conducted to investigate the prevalence and amphotericin B susceptibility of Aspergillus terreus species complex infections. Methods A total of 370 cases from 21 countries were evaluated. Results The overall prevalence of A. terreus species complex among the investigated patients with mould-positive cultures was 5.2% (370/7116). Amphotericin B MICs ranged from 0.125 to 32 mg/L, (median 8 mg/L). Conclusions Aspergillus terreus species complex infections cause a wide spectrum of aspergillosis and the majority of cryptic species display high amphotericin B MICs.
Subjects
Amphotericin B; Aspergillosis; Aspergillus terreus; Crytic species; In vitrosusceptibility
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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
This work is under a Creative Commons License Attribution-NonCommercial-NoDerivatives 4.0 Internacional